You asked:

what diseases are both pleurisy and splenomegaly symptoms of

  • The diseases that pleurisy and splenomegaly are the symptoms of are Systemic lupus erythematosus and chronic Childhood Arthritis.
  • lupus erythematosus, a connective tissue disease

  • juvenile idiopathic arthritis, formerly known as juvenile rheumatoid arthritis, a most common form of persistent arthritis in children

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