Rheumatoid disease (a combination of rheumatoid arthritis, splenomegaly, leukopenia, pigmented spots on lower extremities, and other evidence of hypersplenism (anemia and thrombocytopenia))
Systemic lupus erythematosus (a chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes)
Pleuritis (inflammation of pleura, the lining of the lung) and Raynaud disease (an idiopathic vascular disorder characterized by bilateral Raynaud phenomenon, the abrupt onset of digital paleness or cyanosis in response to cold exposure or stress) is a symptom (a diagnostic medical sign) of which disease (abnormal condition of a part or whole of an organism, characterized by identifiable symptoms)?
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